Drug Alternative to Surgery for Early Miscarriage
A study in the August 25 New England Journal of Medicine examined the
use of the drug Misoprostol (normally used for stomach conditions)
compared to vacuum aspiration for early miscarriage. 652 women with
1st trimester miscarriage were assigned to either the drug (491 women)
or the surgical procedure (161 women), and followed for whether
expulsion was complete at a certain number of days after treatment.
84% of women were sucessfully treated with the drug, and 97% were
successfully treated with aspiration. Women receiving the drug were
more likely to experience reduced hemoglobin, nausea, vomiting, and
diarrhea. However, 83% of women receiving Misoprostol would recommend
the drug (compared to 83% for aspiration) and 78% would use the
treatment again (compared to 75% for aspiration).
A summary is available from NIH News, and the abstract is available
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